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natita [175]
3 years ago
13

Explain how an unbalanced translocation occurs and how it affects humans.

Biology
2 answers:
anyanavicka [17]3 years ago
6 0
<span>An unbalanced translocation is an abnormality caused by the rearrangement of parts between non-homologous<span> chromosomes. To simplify, unbalanced</span> translocation occurs when a child inherits a chromosome with an incomplete or extra genetic material from parent chromosomes with balanced translocations (an even exchange of genetic material and information with the chromosomes). </span> <span>Diseases such as cancer, infertility, and Down syndrome are caused by chromosomal or unbalanced translocation. In 1938, a paper was published by Karl Sax at the Harvard University Biological Laboratories demonstrating the effects of radiation (particularly in X-rays) to major genetic changes affecting the chromosomal translocations. The study led to the development of the field of radiation cytology. </span>
Stella [2.4K]3 years ago
5 0

It occurs when a child inherits a chromosome with extra or missing genetic material from a parent with a balanced translocation.

Robertsonian translocations can occur.

The arms of the chromosome are not the same proportion as a person with normal chromosomes that do not have a mutation.

Difficulties include reproductive consequences, Down syndrome, congenital heart disease, and learning disabilities.

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