Answer:
Answer explained
Explanation:
a. Overexpression of Axl receptor tyroxine kinase correlates with the decresed patient's overall survival and hence it's inhibition is under process.
AXL TKI BMS777607 treatment increased AXL protein levels after 24 h as observed by Western blot and flow cytometry analysis. Mechanistically, this inhibition-induced AXL cell surface accumulation was neither associated with epigenetic modifications, nor altered transcriptional and translational regulation. Hence this later increased the glycosylated protien abundance in kinase dead mutant. The kinase function blockaging resulted in impaired internalisation which finally incresed the level of proliferation.
An alternative technique may exist in linkage of Axl Tkl to a degradation machinery recruitment unit .
b. Mendelian disorders like cystic fibrosis results from error in the given DNA sequence which can be autosomal dominant and recessive both and also X or Y linked. Mutated gene results in the Mendelian disorders. Whereas in cancer there can be mutation or proliferation of the given cells in a specific area. In cancer cells there is 2.5 times more the mRNA present while 6.2times the DNA and hence the detection and diagnosis automatically becomes difficult as in Mendelian disorders only single sequence needs to be studied at a time .
Because Photosynthesis is the process used by plants and some bacteria to create energy from sunlight. ... Cellular respiration uses glucose, or sugars, from food molecules and turns them into carbon dioxide.
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1. Divergent Plate Boundaries or Constructive Plate Boundaries. This is where two plates separate. Ridges are created when mantle convection rises up beneath it, with extreme heat, the crust will thin, and the igneous material beneath will eventually.
<span>2. Divergent, or destructive plate margins cause volcanoes. As the more dense plate subducts, it will melt at depth and the water driven off, will lower the melting point of the overlying mantle wedge, this will create a type of magma. Volcanic Island Arcs are formed at oceanic-oceanic destructive plate margins. The hot, bouyant magma, is less dense that the surrounding rock, so will rise to the surface, and will collect beneath the plate that hasn't been subducted. It will then, under increased pressure erupt under the sea. Over thousands to millions of years, it will keep erupting, to form islands. </span>
<span>3. Earthquakes are mainly caused at Transform boundaries and Divergent boundaries. At transform boundaries, two plates sliding past eachother, and the build up of friction could lead to earthquakes, if enough stress is built up and then suddenly released, then the energy is released as seismic waves or an earthquake. At divergent boundaries, earthquakes happen along the Benioff zone which is the slope of the subducting plate that is slowly being dragged into the mantle by mantle convection and slab pull. </span>
<span>4. Divergent boundaries cause orogenisis (mountain building). But only the continental-continental margin where two continental plates are colliding. Because they are the same density, they don't subduct, but they buckle, compress and uplift to form mountains. Just like the himilayas, when the Indian plate collided with the eurasian plate.</span>
I would say a beacause tundra is very cold desert snd only certain amount of vegetation can happen
