Injection is a kind of drug administration method that has the highest risk of overdose. This bypasses the digestive system thus enters the bloodstream directly. Examples include morphine and heroin. The increased potency of drugs that enter the bloodstream would then result to lethal overdose.
Explanation: Inhalation is the drug administration method with the highest risk of overdose due to increased potency. Drugs administered by inhalation are usually atomized into smaller droplets and basing on the size of their droplets can penetrate deeply into the lungs which is also a factor that determines the absorptive properties of the drug into the bloodstream. However, relatively few drugs are administered this way because inhalation must be carefully monitored to ensure that a person receives the right amount of drug within a specified time otherwise there is a higher risk of overdose (due to increased potency) when compared with other methods of drug administration such as ingestion, injection etc.
