Question

Marfan syndrome can be caused by mutations in either of two genes, but mutations in one of the genes blocks activity of the other. this means that marfan syndrome demonstrates:

Answer 1

Answer;

-Genetic heterogeneity and epistasis.

Explanation;

-Marfan syndrome is a genetic disorder that affects the body's connective tissue that holds all the body's cells, organs and tissue together.

-Genetic heterogeneity is defined as mutations at two or more genetic loci that produce the same or similar phenotypes. Genetic heterogeneity may be either; allelic heterogeneity, which occurs when a similar phenotype is produced by different alleles within the same gene; or locus heterogeneity, which occurs when a similar phenotype is produced by mutations at different loci.

-A gene is said to be epistatic when its presence suppresses the effect of a gene at another locus. Epistatic genes are sometimes called inhibiting genes because of their effect on other genes which are described as hypostatic.

-From these descriptions the marfan syndrome demonstrates both genetic heterogeneity and epistasis.