Loneliness and social isolation have been linked with premature mortality and with functional decline in older people.
We found that high levels of loneliness, but not of social isolation, increased the risk of becoming physically frail.
Neither loneliness nor social isolation were associated with the rate of change in a more broadly defined frailty index.
Loneliness
Loneliness is a subjective feeling of dissatisfaction with one’s social relationships. Both social isolation and loneliness have been linked with increased mortality [2–4], incident heart disease [5, 6] and functional decline [7, 8]. Social isolation and loneliness tend to be correlated, albeit weakly .
Social isolation :
Social relationships are important for health . Most such research has focused on social isolation or loneliness. Social isolation is defined objectively using criteria such as having few contacts, little involvement in social activities and living alone.
Frailty :
Frailty is a clinical syndrome whose main feature is heightened vulnerability to stressors due to lowered physiological reserves, decline in the ability to maintain homeostasis and impairments in multiple systems
A frailty index score reflects the proportion of potential deficits present The phenotype model defines frailty in physical terms, whereas the cumulative deficit model uses a broader definition of frailty.
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The United States invasion of Afghanistan occurred after the September 11 attacks in late 2001, supported by close US allies. The conflict is also known as the U.S. war in Afghanistan. Its public aims were to dismantle al-Qaeda, and to deny it a safe base of operations in Afghanistan by removing the Taliban from power.The United Kingdom was a key ally of the United States, offering support for military action from the start of preparations for the invasion. It followed the Afghan Civil War's 1996–2001 phase between the Taliban and the Northern Alliance groups, although the Taliban controlled 90% of the country by 2001.
U.S. President George W. Bush demanded that the Taliban hand over Osama bin Laden and expel al-Qaeda; bin Laden had already been wanted by the FBI since 1998. The Taliban declined to extradite him unless given what they deemed convincing evidence of his involvement in the 9/11 attacks and ignored demands to shut down terrorist bases and hand over other terrorist suspects apart from bin Laden. The request was dismissed by the U.S. as a meaningless delaying tactic and it launched Operation Enduring Freedom on 7 October 2001 with the United Kingdom. The two were later joined by other forces, including the Northern Alliance troops on the ground] The U.S. and its allies rapidly drove the Taliban from power by 17 December 2001, and built military bases near major cities across the country. Most al-Qaeda and Taliban members were not captured, escaping to neighboring Pakistan or retreating to rural or remote mountainous regions during the Battle of Tora Bora.
In December 2001, the United Nations Security Council established the International Security Assistance Force (ISAF), to oversee military operations in the country and train Afghan National Security Forces. At the Bonn Conference in December 2001, Hamid Karzai was selected to head the Afghan Interim Administration, which after a 2002 loya jirga (grand assembly) in Kabul became the Afghan Transitional Administration. In the popular elections of 2004, Karzai was elected president of the country, now named the Islamic Republic of Afghanistan.[8] In August 2003, NATO became involved as an alliance, taking the helm of ISAF.[9] One portion of U.S. forces in Afghanistan operated under NATO command; the rest remained under direct U.S. command. Taliban leader Mullah Omar reorganized the movement, and in 2002, it launched an insurgency against the government and ISAF that continues to this day.
The Supremacy Clause of the United States Constitution (Article VI, Clause 2) establishes that the Constitution, federal laws made pursuant to it, and treaties made under its authority, constitute the supreme law of the land
On appeal, the Supreme Court of Arizona held that Miranda's constitutional rights were not violated in obtaining the confession.
During a two-hour interrogation, Miranda confessed to the crimes. Lawyers would contend that Miranda had not been clearly informed of his rights to have a lawyer and against self-incrimination. Their appeal to the U.S. Supreme Court would forever change U.S. criminal procedure
The power of making laws and enforcing them is called jurisdiction
