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Anarel [89]
4 years ago
12

Tumor suppressor genes and oncogenes are implicated in carcinogenesis. However, one can predict whether a gene potentially encod

es for a protein that influences carcinogenesis by examining their mutational profile. You sequence the genome of 4 cancers and identify 3 genes of interest. Which of the following genes has the best potential to an oncogene?
tumor 1 tumor 2 tumor 3 tumor 4
Gene A S24F, N465T R33T T345S, G366R P367E, P368Y
Gene B S34R, F360I S34R V254I S34E, T67Y
Gene C S24F, I322E C255I, E344D S34E, P367E

a..Gene A and C are potential oncogenes
b. Gene B and C are potential oncogenes
c. Gene B is a potential oncogene
d. None of the genes are potential oncogenes
e. All of the genes are potential oncogenes
Biology
1 answer:
disa [49]4 years ago
3 0

Answer: Option A - Gene A and C are potential oncogenes

Explanation:

Oncogenes are genes that contribute to the conversion of a normal cell into a cancerous cell when mutated or expressed at high levels.

From the information provided:

Gene A S24F, N465T R33T T345S, G366R P367E, P368Y and

Gene C S24F, I322E C255I, E344D S34E, P367E

Both gene A and C have two similar sequences which represent potential sites of mutation

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These similarities suggest that the all the living organisms share a common ancestor. The french scientist Jacques Monod statement "Anything found to be true of E. Coli must also be true of elephants." is also based on this notion.

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