The arrangement of homeotic genes along chromosomes of vertebrate and invertebrate animals corresponds to the expression pattern of the genes along the anterior-posterior axis of the developing embryo.
<h3>What are homeotic genes?</h3>
- Homeotic genes are a group of body pattern forming genes which control the development along the anterior- posterior axis of the developing embryo.
- These encode transcription factors which control and specify the genes involved in body patterning. These provide identity to the segments during embryo formation.
- Genes located in the 5’ end act on posterior side whereas the genes on 3’ end act on anterior region.
- Homeotic genes are evolutionary conserved and control body specification, patterning and differentiation.
- The loss of function of any of the gene changes the body pattern and affects the development.
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