Helper T cells are the CD4T cells that are present in the inactive form. These cells have receptors for antigens on their surface. These antigen receptors are called T-cell receptors (TCRs). The function of TCR is to recognize and bind to specific foreign antigen fragments that are presented in antigen–MHC complexes. Different helper T cells have their unique TCRs to recognize a specific antigen–MHC complex. The CD4 proteins of helper T cells also interact with the MHC antigens and help maintain the TCR–MHC coupling.
