PROTO-ONCOGENES are corresponding normal cellular genes to an oncogene that is responsible for normal cell growth and division.
An oncogene refers to a gene that is capable of causing cancer due to damage to the DNA molecule either by virus or other DNA damaging agents. A proto oncogene is the normal version of the gene while an oncogene is the abnormal version of the concerned gene.
Yes, it is okay. you should never change your hypothesis if it was wrong.
Answer:
Crossing over
Explanation:
Please see the attachment
Answer:
The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.
Explanation:
Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.
