Water fills up spaces under ground because it has no natural shape or size water is infinite so it fills the space of the area it is in such as a bath tub the water fills the shape of it or fills the area of it and then when someone get in it adjusts to the shape of them making the water rise
Enzymes bind with chemical reactants called substrates. There may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. In some reactions, a single-reactant substrate is broken down into multiple products.