Answer:
The subjects of a conquered kingdom are not used to living in freedom or standing up for themselves, and are therefore slower to take up arms than are the citizens of a republic. There are three options for the conquering prince: destroy the republic, live there, or set up a puppet government. At the end of the day, Machiavelli seems to favor the first option.
Neurotransmitters work locally and their actions are very fast. Both hormones and neurotransmitters act as chemical messengers in the body. However, neurotransmitters' actions are short-lived while hormones act for longer periods of time. Neurotransmitters are delivered through the bloodstream, whereas hormones are found primarily in the synaptic cleft. Hormones are mostly released by glands, whereas neurotransmitters are made in the cell body of the neuron.
I'm assuming that less hot dogs would be made and therefore the price of hot dogs would increase.