Environmental resistance are things that limit the growth of a population so with that being said yes humans are subjected to environmental resistance. Things like diseases, lack of food, fire, and drought can limit the human population
The effects the had on economy in agriculture and social life. The changed early society by introducing new ideas to the people involved in agriculture. Domesticated animals like dogs and horned cattle were used to improve and simplify agriculture
I believe, what emerson meant with that sentence is we should stop dragging around the past and stop bringing it up.
We couldn't control anything in the pass but we still definitely control the outcome of the future. So rather than complaining about what already happen, we should focus on improving ourselves.
As George is talking to Lennie its a double meaning because he's talking to Lennie as he's talking to himself trying to get the courage to kill Lennie