Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
The structure of plasma membrane makes it selectively permeable allowing it to regulate the passage of substances into and out of the cell. Small nonpolar molecules can easily across the phospholipid bilayer of plasma membrane because it is hydrophobic. Polar molecules and ion cannot easily across the hydrophobic portion of plasma membrane because it is hydrophilic. Polar molecules and ions usually across the plasma membrane with the help of transport proteins.
Answer:
crude oil (petroleum) is the only natural liquid fossil fuel
The overproduction of offspring leads to competition in which only the better adapted organisms survive and reproduce.
Answer:
Well protines come in diffrent shapes, for there diffrent functions. The first level, or primary structure, is the linear sequence of amino acids that creates the peptide chain. In the secondary structure, hydrogen bonding between different amino acids creates a three-dimensional geometry like an alpha helix or pleated sheet. An alpha helix is simply a spiral or coiled molecule, whereas a pleated sheet looks like a ribbon with regular peaks and valleys as part of the fabric. The tertiary structure describes the overall shape of the protein. Most tertiary structures are either globular or fibrous. Generally, nonstructural proteins such as enzymes are globular, which means they look spherical. The enzyme amylase is a good example of a globular protein. Structural proteins are typically long and thin, and hence the name, fibrous. Quaternary structures describe the protein's appearance when a protein is composed of two or more polypeptide chains. Often the polypeptide chains will hydrogen bond with each other in unique patterns to create the desired protein configuration.
some hormones are proteins; and some proteins are involved with digestion, respiration, reproduction, and even normal vision, just to mention a few.
f the three-dimensional structure of the protein is altered because of a change in the structure of the amino acids, the protein becomes denatured and does not perform its function as expected.
Explanation:
