Straightforward, dependable core facility HLA tissue typing service
Using state of the art genotyping technologies as used in HLA typing for organ transplantation
We work with genomic DNA, Saliva, Whole Blood, or Cryopreserved cells
Detailed results typically sent in 3 weeks
typeHLA Tissue Typing Service Overview
Typing technology options
New Next Generation Sequencing (NGS)
PCR-SSOP using Luminex®
(previously called Tier 1)
HLA Class I loci available
A, B and C
(whole Class I panel reported)
A, B, C
(can be ordered individually)
HLA Class II loci available
DRB1, DPB1 and DQB1
(whole Class II panel reported)
DRB1, DRB3,4,5, DPA1*, DPB1, DQA1*, DQB1
(can be ordered individually)
Resolution of typing data
Fully resolved 4 digit (allelic level) typing with no degeneracy for all samples
4 digit (allelic level) typing but with some degeneracy
Features / Restrictions
Only available for ordering whole Class I panel (3 loci) or whole Cass II panel (3 loci) or whole Class I and Class II panel (6 loci)
Can be ordered for each locus individually
Turnaround time (approximate)
3 weeks
Sample formats accepted
gDNA, Cryopreserved PBMCs/other Cells, Blood, Saliva
Report format
Electronic format (PDF, XLS) via secure webserver
Explanation:
Positive feedback occurs to increase the change or output: the result of a reaction is amplified to make it occur more quickly. Negative feedback occurs to reduce the change or output: the result of a reaction is reduced to bring the system back to a stable state.
Answer:
Chemical weathering
Explanation:
Caves are formed by the dissolution of limestone. Rainwater picks up carbon dioxide from the air and as it percolates through the soil, which turns into a weak acid. This slowly dissolves out the limestone along the joints, bedding planes and fractures, some of which become enlarged enough to form caves.
Chemical weathering involves the decomposition of rocks due to chemical reactions between minerals such as calcite with water and gases in the atmosphere (e.g. carbon dioxide and sulphur dioxide). The solution of soluble minerals is particularly important in limestone landscapes.
Solutional caves or karst caves are the most frequently occurring caves. Such caves form in rock that is soluble; most occur in limestone, but they can also form in other rocks including chalk, dolomite, marble, salt, and gypsum.
Essentially, water reacts with carbon-dioxide to form carbonic acid. It then seeps slowly through the roof of the cave, depositing calcium carbonate, which hardens and builds up over time to form a stalactite.
Answer:
the answer is all of the above
2. To focus a microscope using the high power lens you must first in low power center the specimen and make sure it is in focus. Then switch to high power and adjust using the fine adjustment or the smaller knob.
3. It prevents dust from settling on the scope and in the lenses.
