Answer: Glycogen phosphorylase is inhibited in response to an insulin signal in skeletal muscle.
Explanation:During insulin signal in skeletal muscle,the insulin receptor is received by tyrosine kinase following an oxidative reaction. Then it acts as an enzyme that shifts phosphate groups from the nucleotide,Adenosine Triphosphate to tyrosine residues on intracellular target proteins.
Insulin is binded to the alpha subunits causing the beta subunits to form phosphorylase unaided.this is known as autophosphorylation,
catalytic activity of the receptor is then activated.
The receptor activates and form phosphorylase with couple of intracellular proteins, which therefore alters their activity, thus generating a biological response.