<h2><u>Answer:</u></h2>
The correct option is C (Dred Scott)
<h3><u>Explanation:</u></h3>
Dred Scott was a slave and social lobbyist who served a few experts previously suing for his opportunity. His case made it to the Supreme Court (Dred Scott v. Sandford) before the American Civil War.
The American Civil War was a war battled in the United States from 1861 to 1865, between the North and the South. The Civil War is the most considered and expounded on scene in U.S. history.
The Columbus Exchange was a very negative event that had many impacts on natives for what I can see. A very important and major impact this caused was a spread of a disease called smallpox. This disease infected many people part of their community as lead to death in many causing there population to decline quickly. People have even been said to believe that 90% of the natives who got infected with this disease died which can show that it was very deadly. Lucky we do not have to worry about this horrible disease.