Alexander the Great ruled from 331 to 323 BC
<span>Isolationism tends to be borne out of a sense of nativism: that is, the idea that we are the best country among others tends to make us wary of wanting to help other nations. In the '20s, this idea that we shouldn't entangle ourselves in the arguments of other nations led to the US taking an isolationist stance on world diplomatic matters.</span>
Mesopotamia - cuneiform.
If that is what you meant.
