Penicillins disrupts bacterial cell wall synthesis.
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How does penicillin affect bacterial cell walls?</h3>
- Penicillin kills bacteria by inhibiting the proteins which cross-link peptidoglycans in the cell wall .
- When a bacterium divides in the presence of penicillin, it cannot fill in the “holes” left in its cell wall.
- β-Lactam antibiotics, including penicillins, cephalosporins, monobactams, and carbapenems, are distinguished by a lactam ring in their molecular structure and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls.
- Penicillins work by bursting the cell wall of bacteria. Drugs in the penicillin class work by indirectly bursting bacterial cell walls.
- They do this by acting directly on peptidoglycans, which play an essential structural role in bacterial cells.
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