Answer:
Shape of active site changes that's why
Enzymes are affected by temperature. So, as temperature increases, enzymes activities also increases, till optimum temperature is reached. If it goes above the optimum temp, the enzymes becomes denatured or can't function anymore due to change in its active site.
here is the answer of this qquestion
<span>"Repeated drug use and/or alcohol use after a period of improvement from substance abuse is called relapse." Relapse is the term used to describe the return to the drug or alcohol. While recovering from addiction it is common several relapses to occur. This should not discourage the patients.</span>