The formation of ketone bodies in the body generally takes place at the time of deficiency of pantothenic acid. The addition of this vitamin would encourage complete catabolism of fatty acids and thus the production of ketone bodies could be avoided.
Pantothenic acid, also known as vitamin B5, is one of the most essential vitamins in the life of humans. It is essential for making cells of blood, and it assists in transforming the food one eats into energy.
I go with Ice Core examples since early sociteties probably didn't have Written Records or maps, and tree rings would only tell if they were fossilized. I hope this helped :)
