(Assuming you meant, 'things', I will answer the question accordingly)
Well, the themes are still the same. The only difference may be the language. Shakespeare used old English (also known as early English). That is why we need a translation for some parts of his plays.
Also, back then, it was mostly about the monarchs, kings, queens, etc. So they had a different way of doing things.
However, the themes still remain common to us today, which makes his work unique and interesting.
Hope this helps. Comment for more help if needed. :)