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Fiesta28 [93]
3 years ago
12

Approximately how much surface area does this organ cover

Health
1 answer:
White raven [17]3 years ago
5 0

Answer:

Skin is the largest organ and covers a surface area of 20 square feet.

Explanation:

Skin has three layers the epidermis, the dermis and the hypodermis. the epidermis is the outermost layer and provides a water-proof barrier. The dermis contains hair follicles, connective tissue and sweat glands. The hypodermis is the subcutaneous deeper layer made up of connective tissue and fat.

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. How do the UV rays cause damage? What exactly causes the skin to burn; can you please be more specific about this mechanism? 
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1. How do the UV rays cause damage?

UV rays cause a dimerization of the pyrimidines at the level of the genome (DNA).

The aromatic rings of the bases constituting the DNA molecule absorb the energy of photons associated with a wavelength of between 230 and 290 nm, ie in the UVC domain and, to a lesser extent, that of UVB. The energy absorbed at two adjacent pyrimidines (cytosine (C) or thymine (T)) provides the energy necessary for the formation of a covalent bond between these two bases, to the detriment of the hydrogen bonds established between two complementary bases and ensuring the cohesion of the double helix of DNA.

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The burns are due to the too intense absorption of the sun rays.

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Mechanism of photosensitive medications

- Photosensitization consists of a cutaneous reaction occurring during exposure to light.

- The mechanisms of photosensitization reactions differ in:

-> Phototoxic reaction, non-immunological, occurring in principle in all individuals, under two conditions:

* presence in the skin, in sufficient quantity, of a substance endowed with a phototoxic potential;

* light exposure of the skin by an effective wavelength at sufficient dose.

-> Photoallergic, immunological reaction, which is a cell-mediated delayed Type IV hypersensitivity reaction. It occurs only in predisposed subjects and does not take into account either the concentration of the molecule or the radiation dose.

-> Sometimes the origin of photosensitization is idiopathic; the photosensitizing agent is not known; this is the case of lucites.

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Here are the main families of photosensitizing drugs, sorted by order of frequency of photosensitization reactions.

* Antibiotics of the quinolone class

* Medicines containing amiodarone

* Diuretics containing sulfonamides

* Antidepressants and neuroleptics: ...

* Cholesterol treatments

* Anti-inflammatories containing ketoprofen, especially in the form of cream.

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