Meissner's corpuscles or corpuscles of touch are a type of nerve endings in the skin within the epithelium that are responsible for sensitivity to fine touch. They have the highest sensitivity (the lowest response threshold) when they receive vibrations of less than 50 Hz, which is what the specifics do. They are rapidly active receptors.
Pacinian corpuscles are mechanoreceptors with very fast adaptation rate that have small receptive fields that respond to deep pressured vibrations. They are found deep in the hairless skin of mammals. They are one of the many receptors in the human body and they are fast adapting because they react to pressure on the skin of mammals.
Pacinian corpuscles is one of the four major mechanoreceptors in the body. Others include,
Meissner corpuscles, Ruffini endings, and Merkel cell neurite complex.
The Bottleneck effect is when species go through an event that reduces its population. The ones that survive have reduced genetic diversity compared to the original population since fewer individuals means there are fewer genotypes.
A glucose molecule enters glycolysis in the cytoplasm of the cell. The glycolytic reactions break down one molecule of glucose into two molecules of pyruvate. Each of the pyruvate molecules is then decarboxylated and is oxidized into acetyl CoA. Acetyl CoA enters Kreb's cycle. Acetyl CoA is completely broken down into CO2 and H2O in Kreb's cycle. In this way, glycolysis and Kreb's cycle break down the glucose molecule into CO2 and H2O in a stepwise manner.
Promoter sequences/region is where the transcription factors and RNA polymerase must attach before the gene can be transcribed. SO if we mutate this sequence, the transcription factors and RNA polymerase won't recognize it thus would not attach and transcribe the targeted gene.