Question

Place the following events in activation of a B cell by a microbe in the order in which they would occur.

Answer 1

Answer:

The proper order is as follows-

1) A B cell differentiates from a lymphocyte stem cell, and the mature B cell expresses a specific type of B cell receptor on its cell membrane.

2) Gene expression is altered in the B cell, and the B cell begins to divide.

3) Several rounds of division occur, producing many B cells that all express the same B cell receptor.

4) The B cell's BCR (B cell receptor) binds to a foreign antigen with high specificity and high affinity.

5) Second messenger signaling is activated in the B cell.