somatic hypermutation occurs only in the <u>V or Variable</u> regions of rearranged heavy and light chains.
Somatic hypermutation occurs only in activated B cells, not T cells. This occurs in germinal establishments inside of lymph nodes and the spleen, where B cells are stimulated and T cells are present. Somatic hypermutation is a procedure in which point mutations pile up at rates 106-fold greater than the background mutation rates observed in other genes in the antibody V-regions of both the light and heavy chains.
Somatic hypermutation of immunoglobulin (Ig) genes is important in antibody-mediated immunity. SHM in B cells serves as the molecular foundation for antibody affinity maturation. In this way, SHM plays an important role in optimizing antibody-dependent immune responses.
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Explanation:
A plant cell wall is arranged in layers and contains cellulose microfibrils, hemicellulose, pectin, lignin, and soluble protein. These components are organized into three major layers: the primary cell wall, the middle lamella, and the secondary cell wall
The best and most correct answer among the choices provided by the question is the first choice. The gonad is usuallyf ound in lower plants and produces gametes. I hope my answer has come to your help. God bless and have a nice day ahead!
Answer:
3.
Explanation:
Since the snake was introduced, many species were killed off which severely impacted food chains and webs
Answer:
hydrolysis
Explanation:
Dephosphorylation is the removal of a phosphate (PO43−) group from an organic compound by hydrolysis, so therefore hydrolysis is your answer.