Answer:
3+4+5+11= 56
Step-by-step explanation:
You can do
83 - 5 to find the answer
So that's
78 or
5 + 78 = 83
Answer:
The probability of a successful event is the ratio of the number of successful events to the total number of events. In this case, a successful event is selecting a red marble from the box. The total number of events is the total number of marbles in the box:
Red marbles/Total number of marbles
4/12 divide
=1/3
Answer:The crystal structures of five 6-mercaptopurine derivatives, viz. 2-[(9-acetyl-9H-purin-6-yl)sulfanyl]-1-(3-methoxyphenyl)ethan-1-one (1), C16H14N4O3S, 2-[(9-acetyl-9H-purin-6-yl)sulfanyl]-1-(4-methoxyphenyl)ethan-1-one (2), C16H14N4O3S, 2-[(9-acetyl-9H-purin-6-yl)sulfanyl]-1-(4-chlorophenyl)ethan-1-one (3), C15H11ClN4O2S, 2-[(9-acetyl-9H-purin-6-yl)sulfanyl]-1-(4-bromophenyl)ethan-1-one (4), C15H11BrN4O2S, and 1-(3-methoxyphenyl)-2-[(9H-purin-6-yl)sulfanyl]ethan-1-one (5), C14H12N4O2S. Compounds (2), (3) and (4) are isomorphous and accordingly their molecular and supramolecular structures are similar. An analysis of the dihedral angles between the purine and exocyclic phenyl rings show that the molecules of (1) and (5) are essentially planar but that in the case of the three isomorphous compounds (2), (3) and (4), these rings are twisted by a dihedral angle of approximately 38°. With the exception of (1) all molecules are linked by weak C—H⋯O hydrogen bonds in their crystals. There is π–π stacking in all compounds. A Cambridge Structural Database search revealed the existence of 11 deposited compounds containing the 1-phenyl-2-sulfanylethanone scaffold; of these, only eight have a cyclic ring as substituent, the majority of these being heterocycles.
Keywords: crystal structure, mercaptopurines, supramolecular structure
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Chemical context
Purines, purine nucleosides and their analogs, are nitrogen-containing heterocycles ubiquitous in nature and present in biological systems like man, plants and marine organisms (Legraverend, 2008 ▸). These types of heterocycles take part of the core structure of guanine and adenine in nucleic acids (DNA and RNA) being involved in diverse in vivo catabolic and anabolic metabolic pathways.
6-Mercaptopurine is a water insoluble purine analogue, which attracted attention due to its antitumor and immunosuppressive properties. The drug is used, among others, in the treatment of rheumathologic disorders, cancer and prevent
Step-by-step explanation:
Answer:
Minimum value of function 
is 63 occurs at point (3,6).
Step-by-step explanation:
To minimize :
Subject to constraints:
Eq (1) is in blue in figure attached and region satisfying (1) is on left of blue line
Eq (2) is in green in figure attached and region satisfying (2) is below the green line
Considering 
, corresponding coordinates point to draw line are (0,9) and (9,0).
Eq (3) makes line in orange in figure attached and region satisfying (3) is above the orange line
Feasible region is in triangle ABC with common points A(0,9), B(3,9) and C(3,6)
Now calculate the value of function to be minimized at each of these points.
at A(0,9)
at B(3,9)
at C(3,6)
Minimum value of function is 63 occurs at point C (3,6).
