Answer:
Nitrogenous bases contain the genetic information, their amount is variable among different species, and the arrangement of these bases is also variable among different species
Explanation:
Both Watson-Crick and Pauling's DNA models considered that DNA nitrogenous bases (i.e., Adenine, Cytosine, Thymine and Guanine) contain the genetic information that determines the characteristics of living organisms. Moreover, both DNA models also considered that nitrogenous base composition varies between species, as well as the arrangement of these bases in the DNA chain also varies between species. Based on these features, Linus Pauling considered that a model where nitrogenous bases would be arranged on the outside of the DNA molecule would be easier for the DNA molecule to be replicated, transcribed, or repaired. Although incorrect, Pauling's DNA triple helix model was fundamental to develop the helical (double-stranded) structure of DNA, which was finally discovered by Watson and Crick in 1953.
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Mitosis
Mitosis is the part of the cell cycle in which the duplicated genetic material (chromosomes) within the parent’s cell nucleus is separated to produce two daughter cells that are genetically identical to the parent. Mitosis is important to life because it is involved in the production of new cells for growth and to replace damaged cells. Mitosis occurs in five stages which are; interphase, prophase, metaphase, anaphase and telophase (cytokinesis).
Established on the data, sickle cell hemoglobin displays altered primary structure and altered quaternary structure; the secondary and tertiary structures may or may not be altered. The sickle cell disease is a cluster of disorders that disturbs hemoglobin, the molecule in red blood cells that transports oxygen to cells all over the body. A person with this disorder have uncharacteristic hemoglobin molecules named hemoglobin S which can interfere with red blood cells into a sickle or crescent shape.