Question

Between your evening meal and breakfast, your blood glucose drops and your liver becomes a net producer rather than consumer of glucose. Describe the hormonal basis for this switch, and explain how the hormonal change triggers glucose production by the liver.

Answer 1

Answer:

Insulin and glucagon are two important hormone involved in regulation glucose levels in the body.

Explanation:

The main role is played by glucagon. Glucagon is an hormone secreted by pancreas in response to drop in glucose levels. It converts stored glycogen present in liver into glucose. It also synthesizes glucose from amino acids. Glucose consumption of liver is reduced to increase the glucose level in the blood. Glucagon also activates glycogen phosphorylase to stimulate the process of gluconeogenesis.

Answer 2

Glucose production by liver

Explanation:

• Most of this secretory organ comprises of acinar or exocrine cells that discharge the pancreatic juice containing stomach related compounds, for example, amylase, pancreatic lipase, and trypsinogen, into the pipes, that is, the fundamental pancreatic and the extrapancreatic channel
• The endocrine cells are bunched together, along these lines shaping the supposed islets of Langerhans, which are little, island-like structures inside the exocrine pancreatic tissue that represents just 1–2% of the whole organ
• drop in glucose triggers the arrival of glucagon by the pancreas. in the liver, glucagon enacts glycogen phosphorylase by animating its cAMP-subordinate phosphorylation and invigorates gluconeogenesis by bringing down [fructose 2,6 bisphosphate] consequently animating FB Pase-1