A. they arose out of Africa less than 200,00 years ago
Answer:
So that oxidation of pyruvate can take place in mitochondria.
Explanation:
Pyruvates is produced in the glycolysis process which occurs in the cytoplasm. So pyruvate is produced in the cytoplasm of the cell. Pyruvate is produced by partial oxidation of glucose and to be fully oxidized it has to enter in the mitochondria.
So after entering the mitochondria the pyruvate first converts into acetyl CoA than this acetyl CoA enters in the citric acid cycle and fully oxidized into CO2. This oxidation generated NADP and FADH2 which provide reducing power during oxidative phosphorylation.
Answer:
α‑ketoglutarate dehydrogenase
Explanation:
This is an enzyme complex ,which is analogous to pyruvate dehydrogenase. . Its catalytic activity is inhibited by it products succinyl Co A,it is also refers to as oxoglutarate dehydrogenase complex.(OGDC).
This enzyme complex is similar to pyruvate dehydrogenase in having the same subunit structure, and using the same type of co-enzyme.