Answer:
Nuclear receptors (NRs) are a class of proteins responsible for sensing steroid and thyroid hormones and certain other molecules. There are 48 genes in the human genome that code for the NRs. The myriad molecular pathways modulated by NRs including but not limited to inflammation, lipid metabolism, apoptosis, extracellular matrix regulation, energy metabolism, and angiogenesis.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/Nuclear-Receptor-Screening-Assays.html
Explanation:
Answer:
ATP is responsible for cocking (pulling back) the myosin head, ready for another cycle. When it binds to the myosin head, it causes the cross bridge between actin and myosin to detach. ATP then provides the energy to pull the myosin back, by hydrolysing to ADP + Pi.
Answer: 3. in the icecaps. 2. temperature. 1. the second one
Explanation:
Answer:
The type of mutation responsible for changing a base in the mRNA strand, without changing the coding aminoacid or protein, is called a <u>silent</u> mutation.
Explanation:
In a silent mutation occurs the change of a nitrogenous base in one of the codons that encodes an aminoacid, without changing the aminoacid or altering the structure or function of the protein to be synthesized.
In this type of mutations the change of the base does not mean the change of the aminoacid, because some aminoacids can be coded with more than one codon. In the case of Leucine, the codons that encode it are CUU, CUC, CUG or CUA, so even if a base changes, the final protein will be the correct one.
For the other options:
- <u><em>Missense</em></u><em>: the change of the base in the DNA chain implies the change of the codon in the mRNA and of the encoded aminoacid, in that way a structural and functional alteration of the synthesized protein occurs. </em>
- <u><em>Nonsense</em></u><em>: the change in the nitrogenous base in the DNA leads to the coding of a termination codon, so that the protein is ultimately incomplete.</em>
- <u><em>Insertion</em></u><em>: in this case there is the addition of more nitrogenous bases to the DNA chain, with respect to the original one.</em>
Current estimations are that one in five Americans will develop skin cancer in their lifetime. It is estimated that approximately 9,500 people in the U.S. are diagnosed with skin cancer every day. Which adds up to over 3.3 million persons each year.
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