<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
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Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
D.it is surrounded by a cell membrane
Clown fish do reproduce sexually because there are both female and maleparts involved to it and spern and a egg unite.
Answer:
- These are water bodies formed from melting glaciers
- However, their size can vary from a few square meters to thousands of square kilometers
- They can be seasonal, existing for a few months or exist for hundreds of years or more
Explanation:
The lakes and the ponds are freshwater bodies of water. They can be formed in numerous different ways, from melting of glaciers, rivers flowing into closed valleys, changes in the geography of a space, increased amounts of precipitation. They can vary in size, and there are ponds and lakes that are very small, just few square meters, or to be thousands of square kilometers in size. Some of the lakes and ponds tend to be seasonal, unlike the majority that are existing throughout the whole year, and the reasons for this are the climate and the manner in which they form. Some lakes can be very old, millions of years of age, like the Ohrid Lake in Macedonia, which is also the most important lake in the world from biogeographical stance of point, and it is considered as one of the most attractive ones in the world as well.
