Answer: The number of available symptomatic treatments has markedly enhanced the care of patients with Amyotrophic Lateral Sclerosis (ALS). Once thought to be “untreatable”, patients with ALS today clearly benefit from multidisciplinary care. The impact of such care on the disease course, including rate of progression and mortality, has surpassed the treatment effects commonly sought in clinical drug trials. Unfortunately, there are few randomized controlled trials of medications or interventions addressing symptom management which has resulted in the need for physicians to base their selection of specific therapies upon personal experience and anecdotal reports (1 Forshew). In this review, we will provide the level of evidence, when available, for each intervention that is currently considered “standard of care” by consensus opinion.
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Explanation:
Inflammation plays a very important role in atherosclerosis progression, due to the fact that it separates and identifies the stage of the plaque. Stable plaques are characterized by a chronic inflammatory infiltrate, while on the other hand vulnerable and ruptured plaques are represented by an ongoing inflammation which causes the fibrous cap to thin out and may lead to that plaque rupturing.
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Your mama
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your mama is nice, !!! 6965
The repolarization or falling phase is caused by the slow closing of sodium channels and the opening of voltage-gated potassium channels. As a result, the membrane permeability to sodium declines to resting levels.
