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Vaselesa [24]
3 years ago
7

The chain termination method of sequencing:

Biology
1 answer:
Cloud [144]3 years ago
5 0

Answer:

Labeled ddNTPs

Explanation:

The chain termination method or sanger method consist in 4 synthetis reaction at the same time. Each of them with a different labeled ddNTPs (ddATP, ddCTP, ddGTP and ddTTP) as part of it sythesis sustract. As the reaction goes on, if a ddNTP is added to the new DNA chain, it will stop the elongation becouse DNA polymerase activity depends on the presence of -OH extremes which are miss on ddNTPs.

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