Answer:
It affected the Americans positively long terms, but negatively in the early times of the exchange.
Explanation:
The Columbian Exchange greatly affected America, bringing destructive diseases that depopulated the Americans but did distribute a wide variety of new crops and livestock throughout the American farm industry. In the long term, this rather increased the human population but still very profoundly affected the Americans.
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For Italy, they were spies who collected top secret knowledge for the Allied Powers. They were U.S. soldiers who fought off the enemy successfully. They were British troops leaving their units to join the enemy.