Answer:
Thermosensitive liposomes (TSL) are promising tools used to deliver drugs to targeted region when local hyperthermia is applied (∼40–42°C) which triggers the membrane phase transformation from a solid gel-like state to a highly permeable liquid state. Selective lipid components have been used to in TSL formulations to increase plasma stability before hyperthermia and speed drug release rate after. Two generations of TSL technology have been developed. The traditional thermal sensitive liposomes (TTSL) have utilized DPPC and DSPC as a combination. The second generation, lysolipid thermally sensitive liposomes (LTSL) technology, has been developed with incorporation of lysolipids that form stabilized defects at phase transition temperature. LTSL maintains certain favorable attributes:
High percentage of lysolipids incorporation;
Minimum leakage for therapeutical drugs encapsulation;
Ultrafast drug release upon heating (3.5 times enhanced compared to TTSL). For example, ThermoDox, a commonly used LTSL drug for cancer, has been reported to release 100% of the encapsulated doxorubicin within 30s;
First and most successful formulation for intravascular drug release.
Explanation:
https://www.creative-biostructure.com/Lysolipid-Thermally-Sensitive-Liposomes-Production-612.htm
<h3><u>Answer;</u></h3>
C) P and Q have similar binding properties
<h3><u>Explanation;</u></h3>
- <u><em>Enzymes are biological catalysts that speeds up chemical reactions. Substrates are substances that are acted on by an enzyme to form a product.</em></u>
- <u><em>An enzyme catalyzed reaction occurs when the substrate binds to the active site of an enzyme to form and enzyme-substrate complex. </em></u>
- <em><u>Substrate P and Q are structurally similar which means they are in a position of binding and fitting in the active site of an enzyme. The strong structural similarity means that the binding properties of these two different substrates may be similar. </u></em>
- <em><u>Formation of similar products or results when acted upon by an enzyme mean they are similar in terms of their binding properties, and thus the production of similar product.</u></em>
Answer:
D) Water temperature decreases; copper temperature increases
Explanation:
The temperature is a way of describing how much heat something has. Because the temperatures of the two substances are not the same, the heat is going to want to travel to the substance with less heat. Therefore, since the copper has less heat than the water, the heat will be transferred to the copper. Remember that this heat is now leaving the water. This increases the temperature of the copper and decreases the temperature of the water.