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dedylja [7]
3 years ago
7

Your first cousin died of tay-sachs disease (autosomal recessive, incidence 0.09%). you are not affected, nor is anyone else in

your extended family. what is the chance that you are a carrier?
Biology
2 answers:
AlexFokin [52]3 years ago
5 0
<span>25%

   Starting from my First cousin family, I know for sure that the Uncle is is a carrier (Aa) and he must have married a wife who is also a carrier (Aa) and that is how they got an affected son. Thus, this leads to the fact that either both of my grandparents are carriers (Aa x Aa) or only one of them is a carrier (Aa x AA). As a result, the chances that my mom (who is related to the uncle who has a defected child) is a carrier is either (2/3 or 1/2) depending if my grandparents genotype, respectively. Thus, if my mom chances of being a carrier is 1/2 then my chance of being a carrier is 1/4. (given that my dad is not a carrier b/c CF is a rare disease) However, if my mom chance of being a carrier is 2/3 then my chance of being a carrier is (2/3)x(1/2)=(1/3) As a result, I could either be 1/4 or 1/3. But since the answer only provide the choice of 1/4 and not 1/3. This leave 25% is the correct answer.</span>
xeze [42]3 years ago
5 0

he opportunity to become a carrier is 25%. Because Tay-Sachs can only happen if both of your parents have the defective gene. Meanwhile, the infected Tay-Sachs is your cousin. then you may just be a carrier so you do not suffer from Tay-Sachs.

<h2>Further Explanation </h2>

Tay-Sachs disease may be a rare hereditary disease that progressively destroys nerve cells (neurons) within the brain and medulla spinalis. This disease is that the oldest fat reserve disease medically reported in 1881.

Causes of Tay-Sachs

Tay-Sachs may be a inherited disease caused by a defective gene. This damaged gene causes the body can't make the protein hexosaminidase A. Without this protein, chemicals called gangliosides can accumulate within the nerve cells of the brain and destroy brain cells. Because the explanation for Tay-Sachs is hereditary, so Tay-Sachs may be experienced if you've got a family or parents with Tay-Sachs gene abnormalities.

Symptoms of Tay-Sachs

1. Symptoms of Tay-Sachs in infants, including:

  • Hearing loss
  • Experience progressive blindness
  • Decreased muscle strength
  • A surprising increase in response
  • Paralysis or loss of muscle function
  • Muscle stiffness (loss of elasticity)
  • Delay in mental and social development
  • Slow growth
  • There are red spots on the eyes

2. Tay-Sachs symptoms in adolescents and adults, including:

  • Weak muscles
  • Speech disorders like slurred
  • Unstable gait
  • Brain memory problems
  • Tremor

Learn more

Definition of Tay-Sachs brainly.com/question/7578005

Symptoms of Tay-Sachs brainly.com/question/7578005

Details

Grade: College

Subject: Biology

keywords: Tay-Sachs

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