Natural selection acts directly on those gene variations for traits or phenotypes.
The phenotype of an organism is the physical characteristic and is determined by the organism's genotype. Natural selection selects the genes that produce a certain phenotype by providing suitable conditions for a certain phenotype.
Answer:
Chronic Kidney Disease - Learn about the causes, symptoms, diagnosis ... Chronic kidney disease is a slowly progressive (months to years) decline in the kidneys' ability ... the kidneys cannot absorb water from the urine to reduce the volume of urine ... in the blood can damage nerve cells in the brain, trunk, arms, and legs