Answer:
Genes coding for proteins involved in chiasma formation.
Explanation:
Chiasma is the connecting link between two non sister chromatids from homologous chromosomes. At chiasma chromosomal crossover takes place in which the genetic material is exchanged between the chromatids. During meiosis aneuploidy occurs if chiasma is absent or impaired due to a mutation in genes encoding for proteins involved in chiasma formation.
Aneuploidy is characterised by presence of abnormal number of chromosomes in cells. They can be 45 or 47 in number apart from the usual 46. Due to impaired chiasma, chromosome pair fails to separate and is passed on to the egg or sperm as it is hence there is one gamete with an extra chromosome and one gamete with a less chromosome. Aneuploidy can result in many genetic disorders like three copies of chromosome 21 can result in Down syndrome.
Answer:
The correct answer would be a lipid-soluble signal.
Signal transduction refers to the set or cascade of bio-chemical reactions take place in a cell in order to transmit the chemical or physical signal from outside the cell to inside target molecule.
It is usually initiated by receptors present on the membrane of the cell which sense the extracellular stimulus (such as ligand, hormone, pressure, temperature, pressure etc). Once activated, these receptors activate the cascade of reaction which ultimately reaches the target molecule and produces a cell's response.
In contrast, the lipid-soluble signals (such as steroidal hormones, thyroid hormone etc) enter the cell membrane without any hindrance. They directly bind to intra-cellular receptor present in the cytoplasm or on the nuclear membrane.
The hormone-receptor complex then enters the nucleus and act as transcription factor and produces the response in the form of transcription.
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