Because it is easily accessible and has a mild immune response, the retina makes a good target for gene therapy.
- In a mouse model, the inner retina was highly effectively transduced by an intravitreally injected adeno-associated virus (AAV) vector.
- The vitreous and internal limiting membrane (ILM) operated as obstacles to transduction in large animals, reducing the efficacy of retinal transduction.
- Before administering AAV vectors, we performed vitrectomy (VIT) and ILM peeling on cynomolgus monkeys to get around these obstacles.
- The findings suggest that surgical ILM peeling prior to AAV vector delivery would be beneficial for retinal disease treatment and safe for effective transduction of the nonhuman primate retina.
Learn more about the adeno-associated virus (AAV) with the help of the given link:
brainly.com/question/28205495
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<span>sulfuric acid - acid rain. Damages forests, limestone statues/buildings, lakes (alters pH) etc. Sulphur trioxide is a pollutant, which is also detrimental to health. Mark me the brainiest!</span>
Answer:
electrons
Explanation:
bc i know big brain stuff
The answer is B
Here is a small experiment you can do to test this.
<span>
Put a pot of water on the stove and bring it to a boil. Take a dry lid and cover it for a minute, and lift the lid up. What happens?
What should happen is that the water droplets run down the lid and fall back into the pot.</span>
