Genes are typically hundreds or thousands of base pairs in length because they code for proteins made of hundreds or thousands of amino acids. Most genes contain the information needed to make functional molecules called proteins.
DifferentDifferent amino acid produce different proteins based on the bonds formed between them .
<h3>How does the sequence of amino acids affect the functions of protein ? </h3>
The sequence of amino acid of a protein determines protein shape , since the chemical properties of each amino acids are forces that gives rise to intermolecular interaction to begin to create secondary structure .
Amino acids are monomers of protein. So , different amino acids produce different proteins based on the bonds formed between them.
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Confirm that the sample has both helicase and primase activities, but not the ability to synthesize DNA
- The replisome is a multiprotein-RNA complex that is required for the replication of DNA. The replisome consists of different proteins which include:
1. Helicase enzymes that unwind and separate the DNA strand
2. Replication factor C (RFC), a DNA-dependent ATP that acts as an activator of DNA polymerase.
3. Proliferating cell nuclear antigen (PCNA)
4. DNA gyrase/topoisomerase that cuts and reseals DNA strands, which is essential for DNA synthesis.
5. Primase enzyme that synthesizes short RNA fragments called primers.
6. DNA polymerase III, an enzyme that catalyzes the polymerization of deoxyribonucleotides into a DNA strand.
7. DNA ligases enzymes that form phosphodiester bonds at a single-strand break in DNA
- A primosome is a multiprotein complex responsible for creating RNA primers on single-stranded DNA (ssDNA) during the replication process.
- The primosome is composed of different primase and helicase enzymes. In<em> Escherichia coli</em>, it consists of PriA helicase, PriB, PriC, DnaB helicase, DnaG (encoded by the dnaG gene), DnaC and DnaT primase.
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