A 40-year-old man who is morbidly obese and leads a sedentary lifestyle has recently been diagnosed with type 2 diabetes. Which
aspects of the man’s obesity likely contributed to his new health problem? A)The low metabolic needs of adipose tissue mimic a hypoglycemic state and suppress insulin secretion.
B)Free fatty acids (FFAs) contribute to problems such as beta cell dysfunction and insulin resistance.
C)Fat tissue initiates glycogenolysis and reliance on glycogen release rather than metabolism of free glucose.
D)Triglyceride deposits in the pancreas result in damage to beta cells.
Free fatty acids contribute to the problems as these are involved in regulating the beta-cell equilibrium that leads to the beta cell dysfunction in a higher level of free fatty acids and increases the risk of obesity and type 2 diabetes.
Higher free fatty acids in the blood caused resistance to the insulin by disturbing the transport of the glucose into the muscles.
