To solve this, you first plug in the 4 and 2 where the x and y's go, making the expression (4 - 2(2))*(4 + 2(2)). Then you solve each parenthesis (below).
(4 - 2(2))*(4 + 2(2)).
(4 - 4)*(4 + 4).
0*8
0
Hope this helped! If you have any questions, feel free to message me :)
