Question

With the assumption that schmid-type metaphyseal chondrodysplasia is rare, is this type of dwarfism inherited as a dominant or recessive trait and why?

Answer 1

Answer and explanation;

-The nearly one-to-one ratio seen in the offspring suggests it is likely inherited as a dominant trait, with the dwarf parent being heterozygous for the dwarf allele along with the normal parent being homozygous for the normal allele.

-Metaphyseal chondrodysplasia, Schmid type (MCDS) is a type of skeletal disorder in which there is abnormal bone formation at the end of the long bones (metaphyses).  MCDS is caused by a mutation in one of the collagen genes. The MCDS mutation is passed on in an autosomal dominant manner.