The Anti-Federalists were almost all unanimously opposed to the ratification of the Constitution, since they thought that it would create a federal government that would become tyrannical--taking away too much power from the states.
The answer is A job loss in certain local industries
I want to say entrepreneurship, but there's also free economy enterprise, so... I'm gonna go with entrepreneurship.
People settled in Delaware for 2 reasons mostly. One was that Delaware accepted different religions without any discrimination. The second was that the land itself was rich with nutrients and similar things and was great for having farms.