If im not mistaken it should be D simple
Misfortune in this sentence basically means bad luck, or bad timing. It is something bad that the man could not control.
Answer:
[A] A comma <u>cannot</u> be used to correct most run on sentences.
Explanation:
The issue with run on sentences is that commas are used to continue the sentence, making it a run on sentence.
What needs to happen is that a period is used, splitting the run on sentence into multiple sentences.