5'-ACTCGTGA-3'-frameshift mutation (number of nucleotides in a DNA sequence is not divisible by three). deletion, one nucleotide in DNA is deleted, in this case A
5'-ATTACGTGA-3'- base substitution, C is substituted with T
5'-ACTACGTGT-3'- base substitution, A is substituted with T
5'-ACTAAGTGA-3'- base substitution, C is substituted with A
Substitution is a type of mutation in whichonly one base is changed. They can be:
• Nonsense mutations-when substitution leads to the formation of a stop codon instead of a codon
• Missense mutations-when one nucleotide is substituted and a different codon is formed
• Silent mutations-when a nucleotide is substituted and the same amino acid is produced
