Question

Genetic disorders can result when chromatids fail to separate properly. During which phase is this problem most likely to occur?

Answer 1

A. Prophase or anaphase

Answer 2

Answer:

The correct answer is option C. anaphase.

Explanation:

Anaphase is the process that separates the replicated or duplicated chromosomes present in the nucleus of a parent cell into 2 identical daughter cells.

The chromatids are separated by the mitotic spindle structure. The sister chromatids are separated together at their centromeres. Then separated chromatids are pulled by the spindle to different poles of the cell.

If nondisjunction takes place during anaphase of meiosis then this means that one pair of sister chromatids did not separate which results in 2 cells that have an extra copy of one chromosome and 2 cells that are lacking that chromosome.

A trisomy genetic diseases in males is Klinefelter syndrome caused by the availability of 1 or more X chromosomes.

Thus, the correct answer is option C.