Anne Frank, Adolf Hitler and 100 of thousands of Jews
The origin of the word "soporific" would be Latin, since it comes from the Latin root word "sopor", which means sleep. This gives way to the current definition which means to induce sleepiness.
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That should be the scientific revolution. That's when people started abandoning the ideas that the church presented and they started focusing on science. It was then discovered that Earth is not in the center but rather goes around the Sun, and Newton made his laws and science and education flourished during that period.