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svet-max [94.6K]
3 years ago
14

In the past 20 years, the development of NMR technology has expanded its application in the field of drugs from identification o

f chemical structures of drugs in vitro to analysis of drugs and their metabolites in body fluids and tissues. Compared with other analytical methods, what are the characteristics of NM R method?
Biology
1 answer:
Virty [35]3 years ago
3 0

Answer:

(1) the simplicity does not require complicated extraction or derivatization of the sample, thus reducing the error caused by the extraction;

(2) Non-invasive: After NMR analysis, biological samples with limited sampling volume can also be used for other treatments, and even non-invasive analysis can be carried out on the whole organism;

(3) Continuous NMR can dynamically monitor the whole biological system without disturbing all kinds of balances in the biological body and realize in-vivo analysis of drugs;

(4) The high resolution N MR spectral line is of the order of Hz, which can provide structural information at molecular level;

(5) Multi-objective can detect drugs and their metabolites under the same physical condition without groping for analysis conditions.

Explanation:

http://www.creative-biostructure.com/nmr-services_28.htm

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Suppose the North American plate is moving away from the Eurasian plate at a rate of 2 cm per year. The eastern-most point of No
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The correct answer is - 1,180 km.

North America and Europe move away from one another, though the two plates, the North American and Eurasian are merging together on the other side. Since the rate of moving away is 2 cm per year, and the current distance is 1,184 km between North America and Europe, the distance between them 200,000 years ago was 1,180 km.

To get to the result we only need to multiply the number of years with the annual movement

2 x 200,000 = 400,000

Than divide the result with 100,000, as that is how much cm are in one km

400,000 / 100,000 = 4

And we get 4 km, in this case 4 km less, thus the distance between the two, 200,000 years ago, was 1,180 km.

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