Answer:
(1) the simplicity does not require complicated extraction or derivatization of the sample, thus reducing the error caused by the extraction;
(2) Non-invasive: After NMR analysis, biological samples with limited sampling volume can also be used for other treatments, and even non-invasive analysis can be carried out on the whole organism;
(3) Continuous NMR can dynamically monitor the whole biological system without disturbing all kinds of balances in the biological body and realize in-vivo analysis of drugs;
(4) The high resolution N MR spectral line is of the order of Hz, which can provide structural information at molecular level;
(5) Multi-objective can detect drugs and their metabolites under the same physical condition without groping for analysis conditions.
Explanation:
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