Hormones are a group of chemicals released by exocrine glands

These hormones are directly secreted into bloodstream from where they reach the site.
An increase in the permeability of the cells of the collecting tubule to water is due to an increase in production of ADH. Hormone ADH also called vasopressin is responsible for regulating the amount of water in the blood and is released from the pituitary gland based on signals from the hypothalamus, which detects the water levels of the blood. When too much water is in the blood, the hormone release is decreased and more water is excreted in the kidneys and thus increasing urine output.
<span>The nurse can explain that his hypermetabolic state can be caused by his medications and also his diet. In order to decrease his exacerbation, the patient will have to follow orders given for a good diet and taking his medication in a timely manner.</span>
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Generalist should go in the blank, hope this helps! :)